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Neurosphera iconCenter for Neurology,
Epilepsy and Psychiatry
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Neurosphera iconCenter for Neurology,
Epilepsy and Psychiatry
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ArticleAdded 3 months ago

Parkinson's Disease – What Are the Treatment Options?

Artykuł 6

Parkinson's disease is a chronic condition, and according to current medical knowledge – it is incurable. The number of people suffering from this degenerative brain disease is steadily increasing. It is estimated that in Poland, around 100 thousand people are affected by it. It is more common in men than in women. Currently, there are many types of therapies that help control its symptoms.

Pharmacological Treatment

People with Parkinson's disease have low dopamine levels in the brain. Medications, by increasing its levels or completely replacing it, can help manage symptoms such as difficulty walking, movement issues, and tremors. The main groups of medications prescribed to people with Parkinson's disease include:

  • Levodopa, which is currently the most effective drug for this condition
  • Dopamine agonists (ropinirole, pramipexole, rotigotine)
  • MAO-B inhibitors (rasagiline, selegiline)
  • COMT inhibitors (entacapone, tolcapone)
  • Amantadine
  • Anticholinergic drugs (biperiden, pridinol)

After starting treatment, patients may experience significant improvement in their well-being. Usually, after 3-5 years (the so-called honeymoon period), as the disease progresses, the benefits of medication may become less visible, and after taking higher doses of Levodopa, involuntary movements (dyskinesias) may occur. The patient may then require an adjustment to their treatment or a complete change, including the use of advanced therapies.

Advanced Treatment Therapies

As part of the National Health Fund (NFZ) drug programs, several advanced therapies are available:

  • Duodopa pump
  • Apomorphine pump
  • Deep Brain Stimulation (DBS)

Physiotherapy and Physical Activity for People with Parkinson's Disease

One method of managing the troublesome symptoms of Parkinson's disease is physical activity and undergoing physiotherapy treatments. These improve motor skills and help prevent falls. They also reduce muscle pain associated with Parkinsonian rigidity (muscle stiffness).

Recommended activities include: nordic walking, dancing, swimming, Rock Steady Boxing, a non-contact boxing workout that includes stretching and other exercises, such as Tai Chi.

Clinical Trials

Currently, there is no cure for Parkinson's disease, so research into new and improved treatment methods is essential. Clinical trials are being conducted worldwide. These aim to develop new treatment methods (both symptomatic and for slowing disease progression) and ultimately bring the medical world closer to curing this condition.

Author: Dr. Anna Bochenek